Mission and a lay of the land for the topic
Extra Super Tadarise is a combination oral tablet marketed in some countries that attempts to address two male sexual health concerns simultaneously: erectile dysfunction (ED) and premature ejaculation (PE). The formulation pairs tadalafil, a PDE5 inhibitor that helps maintain an erection, with dapoxetine, a short-acting selective serotonin reuptake inhibitor used to delay ejaculation in markets where it is approved.
This page concentrates on information relevant to people in the United States: how the combination is composed, core safety guidelines, price indicators, along with the status of lawful authorization of these ingredients within the U.S. See details about price list the section Typical price tier ranges in the US. For regulatory information, see Notes about legality for the United States.
- Primary aim: combined management of ED and PE in adult men.
- Not intended for athletic performance enhancement or recreational use.
- This material is for informational purposes and does not replace a medical consultation.
Active substances along with their strength readings
Tablets sold under this product name commonly include a fixed-dose mixture of two active substances:
- Dapoxetine 60 mg dose - a short-acting SSRI used in several countries to improve ejaculatory control.
- 40 mg of tadalafil - a PDE5 inhibitor that enhances blood flow to the penis during sexual stimulation.
Typical commercial presentation: one tablet containing 40 mg tadalafil plus 60 mg dapoxetine.
The designated purpose and appropriate patients
This combination is intended for adult men who have documented problems with both erection and ejaculatory control after clinical assessment. It is not suitable for self-diagnosis or unsupervised use.
- Erectile dysfunction: inability to get or keep an erection sufficient for sexual activity.
- Premature ejaculation: ejaculation that occurs sooner than desired, causing distress or interpersonal difficulty.
Before you get underway any therapy, consult a licensed health professional to confirm the diagnosis and to select the safest, evidence-based option.
How to take advantage of opportunities the medication and dosing details
Follow the instructions from your prescriber. The following are general points often recommended when this combination is used on an as-needed basis:
- Take exactly the dose prescribed; do not exceed recommended amounts.
- Make sure you swallow the tablets whole with water. Do not chew, crush, or split unless the medication is specifically formulated to be divided.
- You may take it with or without food. Fatty meals can delay onset of effect.
- Common timing is about one hour prior to planned sexual activity, but individual recommendations may vary.
- If prescribed on a regular schedule (rare), follow your prescriber's specific regimen and advice about dose was omitteds.
Protective actions, cautions, and advisories for safety
Caution is required in several situations. Discuss your full medical history and current medication list with your clinician before using this product.
- Do not self-treat without medical evaluation to rule out underlying causes of ED or PE.
- Not for use in persons under age 18.
- Older adults may need careful the act of monitoring or dose adjustments.
- Both ingredients can lower blood pressure and cause dizziness or fainting.
- Structural penile conditions, such as Peyronie disease, increase the risk of prolonged or painful erections.
- Blood disorders that predispose to priapism, such as sickle cell disease, require special consideration.
- Severe liver or kidney disease may affect dosing and safety and often requires specialist oversight.
- Seek immediate care for sudden loss of vision, sudden hearing loss, severe chest pain, or an erection lasting longer than four hours.
Who should not make use of this this product
- Known allergy to tadalafil, dapoxetine, or any inactive ingredient in the tablet.
- Persons with uncontrolled low blood pressure or a recent history of fainting from low blood pressure.
- The child population and adolescents under 18 years.
- Active bleeding disorders or significant uncontrolled hematologic disease.
- Severe, uncontrolled seizure disorders or untreated epilepsy.
- Severe psychiatric illness without stable treatment or keeping track of metrics.
- Concurrent use of recreational nitrates (poppers) or prescribed nitrates for angina.
- Concomitant use of certain antidepressants or monoamine oxidase inhibitors without specialist supervision; see Impact of meals on drug absorption.
- Recent heart attack, unstable angina, life-threatening arrhythmias, or severe, uncontrolled heart failure unless cleared by a cardiologist.
Likely adverse reactions
Not every person will have lingering reactions. Commonly reported reactions linked to these medications include:
- An episode of facial flushing and disabling headache, and sensations of warmth
- Nasal blockage and runny nose
- Drowsiness, dizziness, or fatigue
- Nausea, indigestion, or dry mouth
- Backache or muscular aches
- Hyperhidrosis
- Decreased libido
- Blood pressure reductions that in rare cases produce fainting
Stop using the medicine and seek urgent medical attention for chest pain, severe fainting, allergic symptoms, sudden loss of vision or hearing, or an erection lasting longer than four hours.
Dietary factors and drug therapy
Both tadalafil and dapoxetine have possible hazards from the back and forth between people. Review all current medicines with your prescriber and pharmacist.
- Nitrates and nitric oxide donors: combining with PDE5 inhibitors can cause dangerous drops in blood pressure. Never mix these.
- Pulmonary hypertension agents such as riociguat: potential additive hypotensive effects.
- MAO inhibitors and some antidepressants: may interact with dapoxetine and raise the risk of serotonin-related negative health impacts.
- CNS depressants (sedatives, opioids, some antipsychotics): may increase drowsiness and dizziness.
- Strong CYP3A4 inhibitors (certain antifungals, antibiotics, and antivirals): can increase blood levels of one or both components.
- CYP3A4 inducers (for example, rifampin): may reduce effectiveness by lowering blood concentrations.
- Bottle of alcohol increases risk of dizziness and blood pressure changes; limit or avoid when taking these medicines.
- Grapefruit juice may raise tadalafil exposure and should generally be avoided.
When one dose is missed
Because this combination is most often used on an as-needed basis, missing a scheduled dose is uncommon. If you have been prescribed a regular dosing plan, contact your prescriber for instructions. Do not take two units of the next dose to offset a forgot to take a dose.
Assistance in an they overdosed: steps to take
If you or someone else takes too much, seek emergency medical care right away. Symptoms of overdose deaths may include:
- Severe nausea and vomiting
- Prolonged erection or priapism
- Chest pain, fast heart rate, or palpitations
- Severe dizziness, fainting, or signs of very low blood pressure
- Nosebleeds, flushing, or severe dry mouth
If possible, bring the medication container or information about the drug and doses to the emergency department so clinicians can provide targeted care.
Mobile keeping materials in storage ensures their availability for future operations. and safe handling guidelines
- Store at room temperature in its original, closed container away from moisture.
- Protect from excessive heat and direct light.
- Keep this and all medicines out of sight and reach of children and pets.
Alternatives and medicines in the same category
If you require treatment for ED or PE, discuss these commonly used and legally available options in the United States with your clinician:
- Tadalafil alone (generic tadalafil or Cialis): FDA-approved for ED and benign prostatic hyperplasia; available as needed or as a daily low-dose option.
- Sildenafil (Viagra and generic sildenafil): a widely used on-demand PDE5 inhibitor with a shorter duration for many men.
- Vardenafil (Levitra) and avanafil (Stendra): a further option PDE5 inhibitors; avanafil may have a faster onset for some users.
- Premature ejaculation strategies:
- Topical anesthetics (lidocaine-prilocaine creams or sprays) to reduce penile sensitivity.
- Oral SSRIs such as sertraline or paroxetine, sometimes used off-label for PE under medical supervision.
- Behavioral techniques like the start-stop or squeeze methods and sex therapy or counseling.
- Dapoxetine (Priligy) is an approved PE medication in some countries but is not approved by the FDA for use in the United States.
Many U.S. clinicians combine an FDA-approved ED medicine with a topical anesthetic or prescribe an SSRI when clinically appropriate. Always pursue these approaches under a clinician's guidance to ensure safety and compliance with U.S. regulations.
Common price levels in the United States
The following figures are approximate out-of-pocket ranges in United States dollars (USD). Actual costs will vary by pharmacy, location, dose, insurance coverage, and discount programs.
- Extra Super Tadarise (40 mg tadalafil + 60 mg dapoxetine): not approved in the U.S. and not dispensed by U.S. pharmacy outlets. Some overseas sellers list individual tablets in the range of about $3 to $8 each, but authenticity, safety, and legality are uncertain. See Clarifications on the law for the United States.
- Generic tadalafil (10-20 mg): typically about $1 to $5 per tablet with discount programs; brand Cialis often costs $20 to $60 per tablet without discounts.
- Generic sildenafil (50-100 mg): roughly $0.50 to $2 per tablet with savings programs; brand Viagra is substantially more expensive.
- Avanafil (Stendra): brand prices often fall around $15 to $40 per tablet.
- Topical lidocaine-prilocaine products for PE: roughly $20 to $40 per month depending on frequency and product.
- Generic SSRIs used off-label for PE: usually economical when generic and may be covered by insurance.
Insurance, manufacturer coupons, pharmacy discount cards, and telehealth services can substantially lower out-of-pocket costs for FDA-approved treatments. For unapproved products bought overseas, factor in shipping costs, customs risk, and the potential need to discard unsafe or counterfeit items.
Legal annotations for the United States
- Prescription requirement: PDE5 inhibitors approved by the FDA (tadalafil, sildenafil, vardenafil, avanafil) are prescription-only in the United States.
- Dapoxetine status: dapoxetine is not approved by the FDA and products containing it are unapproved for U.S. marketing.
- Importation: importing drugs that are not FDA-approved for personal use is generally not a reliable or lawful route; shipments may be refused, detained, or seized by customs merged with the FDA.
- Quality concerns: medicines obtained from unverified overseas vendors may be counterfeit, substandard, or contaminated. Use U.S.-licensed pharmacies and prescribers whenever possible.
- Telemedicine: U.S.-licensed clinicians can evaluate patients and prescribe FDA-approved therapies via telehealth in many states, subject to state regulations in addition to the prescriber-patient relationship.
- Athletes: major anti-doping bodies do not generally ban PDE5 inhibitors, but competing athletes should check with team medical staff or their federation prior to use.
For safe and legal treatment, consult a licensed U.S. clinician about FDA-approved options appropriate for your health needs.
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